Early Rehabilitation in Patients on Extracorporeal Membrane Oxygenation (NCT05003609) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Early Rehabilitation in Patients on Extracorporeal Membrane Oxygenation
Australia100 participantsStarted 2022-04-27
Plain-language summary
Critically ill patients who require extracorporeal membrane oxygenation (ECMO) are the sickest in the hospital. More patients are surviving but survivors have compromised functional recovery for months or years. This registry-embedded randomised trial aims to determine if early rehabilitation commenced within 72 hours of ECMO is feasible and improves muscle strength and functional status in patients compared to standard practice in a randomised controlled trial of 100 ICU patients. The effect of the intervention on mortality, health status, and function at 180 days will be evaluated, as well as cost-effectiveness. ECMO-Rehab trial is a registry embedded trial and will be utilising EXCEL data.
Who can participate
Age range18 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
✓. Patient is on ECMO and expected to remain on ECMO for at least 24 hours
✓. Patient is aged 18 years or older.
✓. Patient was functionally independent prior to the current admission.
✓. Patient is eligible for Medicare (Australian sites only).
Exclusion criteria
✕. Patient has been receiving ECMO for more than 72 hours.
✕. Patient has been in ICU for more than 5 days.
✕. Patient has suspected or proven primary myopathic or neurological process associated with prolonged weakness or acute brain injury.
✕. Death is deemed imminent by the treating clinician.
✕. Patient has a documented medical diagnosis of cognitive impairment e.g. dementia.
✕. Patient was unable to mobilise prior to this admission.
What they're measuring
1
Modified Rankin Scale
Timeframe: 180 days post randomisation
Trial details
NCT IDNCT05003609
SponsorAustralian and New Zealand Intensive Care Research Centre