Effect of Sleep Deprivation on Breathlessness and Exercise Capacity in COPD

Inclusion Criteria: (All required) * Age 18 years or older * COPD diagnosed by physician in accordance with Global Initiative For Chronic Obstructive Lung Disease (GOLD) guidelines (GOLD 2021), with a spirometric ratio of the forced expired volume in one second (FEV1) / forced vital capacity (FVC) \< 0.7 and a FEV1 \< 80% of predicted post bronchodilator at baseline. * Self-reported average sleep time of six hours or longer during a normal night. * No regular treatment with sleep medication or anxiolytics. * Able to cycle * Able to talk and write Swedish well enough to participate in the study procedures, as judged by the Investigator. Exclusion Criteria: * Resting peripheral oxygen saturation (SpO2) \< 92% * Night shift worker * Hospitalization or clinical instability during the last four weeks * Treatment with supplementary oxygen at rest or during exercise * Sleep disturbance, defined as a Pittsburgh Sleep Quality Index \>5 at baseline * Contraindication to exercise testing in accordance with clinical practice guidelines (ATS/ACCP Statement on cardiopulmonary exercise testing. Am J Respir Crit Care Med 2003; 167:211-277) * Expected survival shorter than six months as judged by the Investigator.