Adjuvant Stereotactic Body Radiation Therapy After Trans-arterial Chemoembolization in Hepatocell… (NCT04996914) | Clinical Trial Compass
RecruitingNot Applicable
Adjuvant Stereotactic Body Radiation Therapy After Trans-arterial Chemoembolization in Hepatocellular Carcinoma
Germany30 participantsStarted 2026-05-05
Plain-language summary
The study investigates the adjuvant SBRT following TACE in early and intermediate stages HCC not amenable for surgical resection.
Who can participate
Age range
18 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* HCC (diagnosis: histological or radiological)
* Age: 18-80
* Number of lesions 1-3 lesions
* Size of the lesion (or sum of 2-3 lesions) ≥ 4 cm
* Sufficient non-tumorous liver volume (≥ 800 cm3)
* Child Pugh Score: A5-6 or B7-8
* BCLC A or B
* Patient is illegible or refused surgical resection or orthotopic liver transplant
* Blood work (within 2 weeks before registration):
* Absolute neutrophil count (ANC) ≥ 1,500 cells/mm³)
* Platelets ≥50,000 cells/mm³
* AST (and ALT) \< 5 times ULN
* Serum creatinine ≤ ULN or creatinine clearance ≥ 50 mL/min
Exclusion Criteria:
* Evidence of extrahepatic disease (lymph node or distant metastases)
* Evidence of macroscopic vascular invasion
* Evidence of an arterio-portal or arterio-venous fistulas
* History of previous malignancy
* Previous SIRT
* Previous Sorafenib in the last 8 weeks
* Pregnant and lactating females
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.