Effect of Trans-Nasal Afferent Loop Decompression on Post-Pancreaticoduodenectomy Pancreatic Fistula

Inclusion Criteria: * Patient scheduled for elective open pancreaticoduodenectomy with Child reconstruction * Age \> 18 years and ≤ 85 years * Full agreement to participate and written informed consent is given Exclusion Criteria: * Emergent pancreaticoduodenectomy * Laparoscopic pancreaticoduodenectomy or robotic pancreaticoduodenectomy, including transition to open approach * Participant in other trials of pancreaticoduodenectomy with interfering interventions and/or endpoints * Patient with severe co-morbidity(s) before surgery, including severe insufficiency in kidney, heart and/or liver, etc. * Patient had medication history of corticosteroids over 3 days during last 30 days before surgery * No need for pancreaticojejunostomy during pancreaticoduodenectomy (i.e. past left pancreatectomy, pancreaticogastrostomy, etc.), or pancreatic anastomosis cannot be reconstructed for any reason * External stenting is used during the surgery for any reason * Nasogastric tube is inserted and kept for postoperative gastric decompression * In any situation that the placement of afferent loop decompression tube is medically inappropriate or not infeasible