OCT Guided Trans Nasal Imaging of the Small Intestine in Adults (NCT04984447) | Clinical Trial Compass
By InvitationNot Applicable
OCT Guided Trans Nasal Imaging of the Small Intestine in Adults
United States30 participantsStarted 2017-09-22
Plain-language summary
The investigators are seeking healthy adult participants 18-60 years and healthy pregnant women in their 2nd trimester of pregnancy for a research study to assess a new imaging device. The Tearney Laboratory at the Wellman Center for Photomedicine at Massachusetts General Hospital is developing high-resolution imaging devices that can be used to improve diagnostics in gastrointestinal diseases.
Who can participate
Age range18 Years – 60 Years
SexALL
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Inclusion Criteria:
* Healthy participants
* Participants who are in their 2nd trimester of pregnancy
* Participant must be 18-60 years of age
* Participant must be able to consent to the procedure.
* Participant must fast (no solid food) for at least 8 hours and have no liquids within 2 hours prior to the procedure.
Exclusion Criteria:
* Participants with a history of upper respiratory disease or surgery
* Pregnant women with high-risk pregnancies such as history of: hyperemesis gravidarum, HIV, severe anemia or any other high-risk pregnancy conditions at the discretion of the subject's physician and the PI
* Participants with a history of upper gastrointestinal surgery
* Pregnant women with Type 1 diabetes
* Pregnant women with Type 2 diabetes on medication and gestational diabetes requiring medication
* Pregnant women with gestational thrombocytopenia
* Participants with upper respiratory infection at least 7 days prior to the procedure
* Pariticipants with any contraindications to the placement of the NJ tube including deviated septum or any other anatomical abnormalities of the nasopharynx or upper gastrointestinal region, history of trans-sphenoidal surgery, facial or cranial trauma and fractures, chronic sinusitis, esophageal strictures, varices etc.
* Participants on medications that delay gastric emptying.
* Participants on drugs which impair clotting like anticoagulants and antiplatelet drugs, NSAIDS, history of bleeding disorders.
* Participants using nasal ster…