DCB Angioplasty for Coronary Lesions: an OCT Analysis

Inclusion Criteria: * Coronary angiography shows that at least one coronary artery has a diameter stenosis \>70% (left main stem diameter stenosis\>50%) * Stable or unstable angina * Availability for follow-up for up to 12 months Exclusion Criteria: * Acute myocardial infarction within 48 hours * Severe calcified lesions * Unable to tolerate dual antiplatelet treatment (DAPT) * Severe abnormal hematopoietic system, such as platelet count of \< 100×109/L or \> 700×109/L and white blood cell count of \< 3×109/L * Active bleeding or bleeding tendency * Severe coexisting conditions, such as severe renal insufficiency (GFR \< 60 ml/min•1.73m2), severe hepatic dysfunction \[elevated ALT (glutamicpyruvic transaminase) or AST (glutamic-oxal acetic transaminase) level by more than three-fold of the normal limitation\], acute or chronic heart failure (NYHA III-IV), acute infectious diseases, immune disorders, malignancy, etc. * Life expectancy \< 12 months * Pregnancy or planning pregnancy * Drug allergies or contraindications to aspirin, clopidogrel, ticagrelor, statins, contract, anticoagulant, stent, etc. * Participation or planning to participate in another clinical trial during the same period * Refusal to comply with the study protocol