The arduous nature of military training and operations require personnel to encounter high heat load, e.g., during intense physical exertion, particularly in the heat. These conditions reduce operational effectiveness and expose personnel to a risk of incapacitation and death from exertional heat illness (EHI). The aim of this study is to examine traditional and novel risk factors that may increase thermal strain and EHI likelihood in military recruits undergoing strenuous physical exercise.
Age range
17 Years – 35 Years
Sex
ALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Body mass index in EHI and control group
Timeframe: Baseline
Fitness in EHI and control group - participants ranked by time to complete fitness test
Timeframe: Baseline
Core temperature in EHI and control group
Timeframe: 1 Day
Heart rate in EHI and control group
Timeframe: 2 Hours
Urine osmolality in EHI and control group
Timeframe: Baseline
Sleep quality and quantity, measured by Pittsburgh Sleep Quality Index, in EHI and control group
Timeframe: Throughout study - up to 1 week
Sleep quality, measured by actigraphy, between EHI and control group
Timeframe: Throughout study - up to 1 week
Sleep quantity, measured by actigraphy, between EHI and control group
Timeframe: Throughout study - up to 1 week
Circulating Interleukin 6 in EHI and control group
Timeframe: Baseline
Circulating C-Reactive Protein in EHI and control group
Timeframe: Baseline
Circulating Creatine kinase in EHI and control group
Timeframe: Baseline
Circulating Aspartate Aminotransferase in EHI and control group
Timeframe: Baseline
Circulating Alanine Aminotransferase in EHI and control group
Timeframe: Baseline
Circulating Claudin 3 in EHI and control group
Timeframe: Baseline
Circulating Zonulin in EHI and control group
Timeframe: Baseline
Circulating Lipopolysaccharide binding protein in EHI and control group
Timeframe: Baseline
Circulating immunoglobulin E in EHI and control group
Timeframe: Baseline
Salivary cortisol in EHI and control group
Timeframe: Throughout study - up to 1 week
Detection of infectious pathogens in EHI and control groups
Timeframe: Throughout study - up to 1 week
Respiratory illness symptomology, measured by Jackson common cold questionnaire, in EHI and control group
Timeframe: Throughout study - up to 1 week
Gastrointestinal illness symptomology, measured by gastrointestinal symptoms questionnaire, in EHI and control group
Timeframe: Throughout study - up to 1 week
Abundance and diversity of gastrointestinal microbiota in EHI and control group
Timeframe: Baseline