This study will compare the current standard-of-care pain treatment regimen options that are available to patients who undergo gender-affirming surgery. The purpose of this research is to determine if any of these options are more (versus less) effective than the others to manage surgery related pain, after surgery.
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Changes in peri-operative pain location and intensity over time, as measured by anatomic pain maps
Timeframe: Any time pain is experienced, starting on the morning of post-operative Day 1 to End of Study at the final post-operative visit (average of 30 days after surgery)
Changes in opioid consumption per 24 hours, measured by total inpatient and total outpatient
Timeframe: Per 24 hours, starting on post-operative Day 1 to End of Study at the final post-operative visit (average of 30 days after surgery)
Change in the opioid side effect of urinary retention, as indicated by time to spontaneous voiding
Timeframe: Post-operative Day 1 to Discharge (average of 7 days after surgery)
Change in the opioid side effect of urinary retention, as measured by a Urinary Bother Symptom Score Questionnaire
Timeframe: Pre-operative visit, Discharge (average of 7 days after surgery), and End of Study/final post-operative visit (average of 30 days after surgery)
Change in the opioid side effect of decreased GI motility and ileus, as indicated by number of post-operative days until commencement of regular passage of flatus
Timeframe: Post-operative Day 1 to Discharge (average of 7 days after surgery)
Change in the opioid side effect of nausea, as indicated by number of post-operative days to toleration of liquid diet and regular diet, as well as reported experience of nausea
Timeframe: Post-operative Day 1 to Discharge (average of 7 days after surgery)
Post-operative length of inpatient stay
Timeframe: Post-operative Day 1 to Discharge (average of 7 days after surgery)
Global satisfaction with respect to pain and physical comfort, as measured by a Quality of Recovery 15-Item Inventory
Timeframe: Daily, starting on the morning of post-operative Day 1 to End of Study at the final post-operative visit (average of 30 days after surgery)
Frequency of treatment complications
Timeframe: End of study (average of 30 days after surgery)