Thorough QT (TQT) Study to Evaluate the Effect of LC350189 on Cardiac Repolarization in Healthy Male and Female Subjects

Inclusion Criteria: * The subject is 18 to 55 years of age, inclusive, with a body mass index (BMI) 18 to 33 kg/m2, inclusive, at screening. * The subject is considered by the investigator to be in good general health as determined by medical history, clinical laboratory test results, vital sign measurements, 12-lead ECG results, and physical examination findings at screening. * The subject is able to provide written informed consent and agrees to comply with all protocol requirements. Exclusion Criteria: * The subject has a history of risk factors for torsades de pointes, including unexplained syncope, known long QT syndrome, heart failure, myocardial infarction, or angina. * The subject has a family history of long QT syndrome, Brugada syndrome, or sudden death. * The subject has a resting HR of \<40 bpm or \>100 bpm when vital signs are measured at screening or check-in. * The subject has history or presence of unstable cardiovascular disease, including myocardial infarction, cardiac arrhythmia, or cerebrovascular disease (eg, cerebrovascular accident/stroke or transient ischemic attack). * The subject has a history of other acute or chronic cardiovascular disease or coronary revascularization surgery (eg, coronary artery bypass graft, percutaneous transluminal coronary angioplasty). * The subject uses a cardiac pacemaker. * The subject has a history of any other medical, psychological, or social condition that, in the opinion of the investigator or the medical monitor,…