UnknownPhase 4

Naldebain and Video-assisted Thoracoscopic Surgery

Taiwan60 participantsStarted 2021-07-07

Plain-language summary

To evaluate the postoperative analgesic effect of combined use of Naldebain® and thoracic paravertebral block in thoracoscopic surgery

Who can participate

Age range

20 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 1\) Subject's age: 20\~65 years old * 2\) American Society of Anesthesiologists (ASA) Physical Status classification: I\~III * 3\) Patients who need postoperative pain relief due to thoracoscopic surgery Exclusion Criteria: * 1\. The patient suffers from a communication disorder * 2\. The patient has coagulopathy * 3\. Sick with obvious heart, lung, liver or kidney disease * 4\. The patient's body mass index is less than 18.5 or greater than 35 * 5\. Pregnant patients * 6\. Patients who took opioids for more than three weeks before surgery * 7\. Patients with contraindications to local anesthesia * 8\. Patients with a history of chronic pain * 9\. Patients with a history of drug allergy to Naldebain

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

postoperative analgesic effect

Timeframe: During the first one hour in the recovery room, the pain intensity was evaluated every 15 minutes.

postoperative analgesic effect

Timeframe: the pain intensity was evaluated at 3 hours after surgery.

postoperative analgesic effect

Timeframe: the pain intensity was evaluated at 6 hours after surgery.

postoperative analgesic effect

Timeframe: the pain intensity was evaluated at 12 hours after surgery.

postoperative analgesic effect

Timeframe: the pain intensity was evaluated at 24 hours after surgery.

postoperative analgesic effect

Timeframe: the pain intensity was evaluated at 36 hours after surgery.

postoperative analgesic effect

Timeframe: the pain intensity was evaluated at 48 hours after surgery.

Trial details

NCT IDNCT04962152

SponsorKaohsiung Medical University Chung-Ho Memorial Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-05-07

Contact for this trial

Hung-Te Hsu, MD, PhD

+88673121101 hdhsu1228@hotmail.com

View on ClinicalTrials.gov More Analgesia trials

Who can participate

Age range

20 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

postoperative analgesic effect

Timeframe: During the first one hour in the recovery room, the pain intensity was evaluated every 15 minutes.

postoperative analgesic effect

Timeframe: the pain intensity was evaluated at 3 hours after surgery.

postoperative analgesic effect

Timeframe: the pain intensity was evaluated at 6 hours after surgery.

postoperative analgesic effect

Timeframe: the pain intensity was evaluated at 12 hours after surgery.

postoperative analgesic effect

Timeframe: the pain intensity was evaluated at 24 hours after surgery.

postoperative analgesic effect

Timeframe: the pain intensity was evaluated at 36 hours after surgery.

postoperative analgesic effect

Timeframe: the pain intensity was evaluated at 48 hours after surgery.