CompletedPhase 3

Efficacy of Fractional Carbon Dioxide Laser Combined With Platelet-rich Plasma

Philippines16 participantsStarted 2019-07-01

Plain-language summary

This study determined the efficacy of ablative fractional carbon dioxide laser combined with autologous platelet-rich plasma versus ablative fractional carbon dioxide laser with placebo in the treatment of striae gravidarum of postpartum Filipino women.

Who can participate

Age range

18 Years – 45 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Postpartum patients with ages 18 to 45 years * Fitzpatrick skin type III-V * having bilateral symmetrical SG of red, white or a combination of both types. Exclusion Criteria: * pregnancy * breastfeeding * heavy consumption of alcoholic beverages * dermatological conditions such as psoriasis, systemic lupus erythematosus and atopic dermatitis * uncontrolled hypertension, diabetes mellitus, heart disease, acute and chronic liver/kidney impairment/disease; * elevated liver function tests (SGPT, SGOT), and serum creatinine; * intake of any medications that may influence the outcome of the study; * intake of any vitamins/minerals or any supplements in the past 6 months; and * application of any topical agents (e.g., whitening, anti-aging) in the past 6 months

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Clinical improvement

Timeframe: 16 weeks

Trial details

NCT IDNCT04956367

SponsorJose R. Reyes Memorial Medical Center

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2019-10-31

View on ClinicalTrials.gov More Striae Gravidarum trials