Regular vs. Clear Liquid Diet for Mild to Moderate Acute Pancreatitis (NCT04932785) | Clinical Trial Compass
UnknownNot Applicable
Regular vs. Clear Liquid Diet for Mild to Moderate Acute Pancreatitis
United States150 participantsStarted 2021-07-18
Plain-language summary
Acute pancreatitis is among the most common gastroenterology diagnosis in the United States, and represents a large economic burden to the United States health system. While recent guidelines agree early feeding shortens length of stay, these guidelines fail to provide recommendations on optimal diet to start leaving diet type to clinician discretion. Therefore, the aim is to assess the comparative efficacy of full calorie regular diet (RD) versus clear liquid diet (CLD) on length of hospital stay (LOHS) for mild to moderate acute pancreatitis (AP). The study population will target mild to moderate acute pancreatitis patients who can tolerate eating in a single institution. The primary end point will focus on LOHS, and secondary end points will include Pancreatic Activity Scoring System, side effects and readmission.
Who can participate
Age range18 Years
SexALL
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Inclusion criteria
✓. \>18 years of age
✓. Presentation with acute pancreatitis as defined by two of three criterion per the Revised Atlanta Criteria guidelines: (a) Amylase or lipase \> 3x the upper limit of normal, b) Classical abdominal pain, c) Ultrasound or computed tomography of unequivocal pancreatitis. Such radiographic findings include swelling, edema, or heterogeneity of the gland or peripancreatic fluid or stranding
Exclusion criteria
✕. Pregnant or breastfeeding women
✕. Incarcerated patients
✕. Patients \< 18 years of age
✕. Patient unable or unwilling to give informed consent
✕. Patients transferred from another hospital
✕. The possibility of poor oral intake for reasons other than acute pancreatitis (e.g. intubation, failure to pass an indicated swallow study for aspiration risk, anorexia secondary to active malignancy, etc)
✕. Surgical intervention for infected pancreatic necrosis or pancreatic hemorrhage
What they're measuring
1
Length of Hospitalization Stay
Timeframe: From date of randomization until the date of discharge, assessed up to 24 months