Fluid challenge is frequently used in fluid management of critically ill patients. Assessing whether there is a preload reserve that can be used to increase the stroke volume by delivering a small amount of fluid in a short period of time. Optimization of fluid therapy is very important in intensive care patients. Inappropriate fluid therapy can cause significant morbidity and even mortality. Increased intracranial pressure is one of these important complications. In the present study, we planned to evaluate the effect of a fluid challenge on intracranial pressure by measuring the optic nerve sheath diameter (ONSD).
Who can participate
Age range18 Years – 80 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
✓. Patients with no known intracranial pathology.
✓. Patients with systolic blood pressure \< 90 mmHg
✓. Patients with mean blood pressure \< 65 mmHg
✓. Patients with tachycardia (heart rate 100 beats/min)
✓. Patients with mottled skin, oliguria (diuresis of less than 20 ml/hr or 0.5 ml/kg/hr for two hours), and acute renal failure.
✓. Patients with arterial lactate concentration \> 2 mmol/L
Exclusion criteria
✕. Patients with known intracranial hypertension
✕. Patients in the early postpartum period
✕. Patients with severe mitral or aortic regurgitation
✕. Patients with cardiac arrhythmia
✕
What they're measuring
1
The change in intracranial pressure associated with the fluid challenge
Timeframe: Before, at the end, and 30 min after the fluid challenge.