UnknownPhase 1/2

Ovarian Injection of PRP (Platelet -Rich Plasma) Vs Normal Saline in Premature Ovarian Insufficiency

Egypt60 participantsStarted 2021-06-20

Plain-language summary

60 cases with premature ovarian insufficiency will be randomized to either receive PRP or saline injection in their ovaries. Then follow up by hormonal \& ultrasound \& clinically to monitor any changes

Who can participate

Age range20 Years – 42 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * PORs who meet at least two of the following three Bologna criteria * AMH: 0.1-1 ng/ml. Exclusion Criteria: * ovarian insufficiency due to gonadal dysgenesis and - * chromosomal abnormalities, * immunoglobulin A deficiency, * the use of anticoagulants, * psychotropic medicaments, * psychiatric disorders, * carcinomas or * a history of chronic pelvic pain. * Women with present infection, * haemoglobin lower than 11 g/L or * platelets lower than 150 x 10ʒ/μL were excluded from the study.