The proposed randomized control trial will evaluate auricular point acupressure (APA) on chemotherapy-induced neuropathy (CIN), rigorously considering point specificity and placebo effects by integrating self-report measures, psychophysical measures (QST), endogenous biomarkers (cytokines), and neuro-imaging to investigate APA's efficacy and underlying mechanism(s).
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Change in pain severity as assessed by the Brief Pain Inventory
Timeframe: Up to 4 months
Change in numbness as assessed by the Brief Pain Inventory
Timeframe: Up to 4 months
Change in tingling as assessed by the Brief Pain Inventory
Timeframe: Up to 4 months
Change in physical function as assessed by Patient-Reported Outcomes Measurement Information System (PROMIS) 29
Timeframe: Up to 4 months