RNF213 Variants and Collateral Vessels in Moyamoya Disease (NCT04906564) | Clinical Trial Compass
CompletedNot Applicable
RNF213 Variants and Collateral Vessels in Moyamoya Disease
China300 participantsStarted 2019-01-01
Plain-language summary
The purpose of this study is to detect the association between RNF213 variants and collateral vessels in patients with moyamoya disease.
Who can participate
Age range4 Years – 60 Years
SexALL
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Inclusion Criteria:
* Written informed consent is obtained
* Patients with age between 4-60 years
* Cerebral digital subtraction contrast angiography (DSA) reveal severe stenosis or occlusion of the distal internal carotid or proximal middle and anterior cerebral arteries with prominent lenticulostriate 'moyamoya collaterals'
Exclusion Criteria:
* There are other vascular diseases, including systemic vasculitis, neurofibroma, meningitis, sickle cell disease, down's syndrome, and previous basilar radiotherapy
* Patients with cardiogenic embolism, including a history of atrial fibrillation, valvular disease or cardiac valve replacement
* Physical or subjective failure to cooperate with the examination or serious comorbid diseases
What they're measuring
1
Identification of RNF213 variants and different types of collateral vessels