Stopped: Business decision and not due to any safety or tolerability concerns.
The purpose of this study is to assess the safety, tolerability, pharmacokinetics (PK), immunogenicity and preliminary efficacy of VAY736 alone or in combination with other therapies in patients with NHL in a platform trial.
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Incidence and nature of dose limiting toxicities (DLTs)
Timeframe: 28 days (first cycle of treatment)
Incidence of Adverse events (AEs) and serious adverse events (SAEs)
Timeframe: 4 years
Number of patients with dose interruptions and dose reductions
Timeframe: 4 years
Dose intensity
Timeframe: 4 years