Placental Volume, Flow, and Vascularity Study (NCT04900207) | Clinical Trial Compass
CompletedNot Applicable
Placental Volume, Flow, and Vascularity Study
United States440 participantsStarted 2021-03-10
Plain-language summary
The purpose of this preliminary study is to implement an automated and standardized computer-based method that accurately measures placental volume, blood flow, and vascularity. This will be accomplished by using the digital data obtained at the time of a first-trimester 3D image volume. This information will then be used to further investigate whether placental volume, blood flow, and vascularity can be used to predict the risk of preeclampsia in conjunction with maternal history and serum blood markers obtained at the time of their ultrasound.
Who can participate
Age range18 Years – 45 Years
SexFEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Singleton gestation
* Qualify for a first-trimester screen at the time of enrollment. Criteria for the screen include pregnancy with gestational age between 10 weeks 3 days and 13 weeks 6 days of gestation as well as a crown-rump length between 40 and 84 mm.
* Complete a first-trimester ultrasound at the qualifying M Health Fairview Maternal Fetal Medicine Clinics, which include University Riverside, Ridges, South Dale, and Health East sites
* Provide a blood sample for either completion of the first-trimester screen and/or for the completion of the research study
Exclusion Criteria:
* Multi-fetal gestation or pregnancy with major fetal congenital anomalies and/or known fetal aneuploidy
* Unwilling to complete a first-trimester ultrasound and/or unwilling to provide a serum sample
What they're measuring
1
Predictive Value of Model for the Development of Preeclampsia