Noninvasive Evaluation of Renal Allograft Fibrosis by MRI (NCT04899167) | Clinical Trial Compass
CompletedNot Applicable
Noninvasive Evaluation of Renal Allograft Fibrosis by MRI
United States22 participantsStarted 2021-08-01
Plain-language summary
The purpose of this study is to validate an MRI method to detect renal fibrosis in patients after kidney transplantation (KT).
Who can participate
Age range18 Years – 80 Years
SexALL
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Inclusion Criteria:
* Age 18-80 years
* Recipient of living donor kidney transplantation 4 or 7 years earlier
* Competent and able to provide written informed consent; Ability to comply with protocol
Exclusion Criteria:
* Patients have clinically significant medical conditions within the prior 6 months before: e.g. myocardial infarction, congestive heart failure, stroke, that would, in the opinion of the investigators, compromise the safety of the patient.
* Severe chronic liver, heart or lung disease
* Undergoing acute rejection
* Contra-indication to biopsy; bleeding disorders
* Chronic infection
* Any active malignancy and undergoing therapy
* Kidney or ureteric stone
* Unable to give valid informed consent
* Known pregnancy or intent to conceive during the study period
* Pacemaker, implantable defibrillator, magnetically active metal fragments, claustrophobia or other contraindication to MRI
* Federal medical center inmates.
* Latex allergy