Comparison of Two FiO2 (1 or 0.5) for Tracheal Extubation in Post-anesthesia Care Unit (NCT04879290) | Clinical Trial Compass
CompletedNot Applicable
Comparison of Two FiO2 (1 or 0.5) for Tracheal Extubation in Post-anesthesia Care Unit
France119 participantsStarted 2021-04-09
Plain-language summary
The purpose of the study is to assess the optimal fraction of inspired oxygen (0.5 or 1) for extubation or removal of a supraglottic airway device after general anesthesia.
Who can participate
Age range18 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients undergoing general anesthesia, with invasive mechanical ventilation including an airway device (supraglottic airway device or tracheal tube) at their arrival in PACU.
* ASA physical status classification 1, 2, or 3 stabilized.
* Surgery performed in emergency operating room department including vascular, digestive, urological and minor trauma surgery or surgery performed in head and neck anesthesia pole block including anterior cervical spine, lumbar disc herniation, cranioplasty, nerve stimulator, vertebroplasty, narrow lumbar canal, simple arthrodesis (less than or equal to two stages), otological, ophthalmological and skin surgery.
Exclusion Criteria:
* Per-operative hemodynamic instability.
* Patients with a BMI greater than 35.
* Patients classified as difficult to intubate and / or ventilate.
* Heavy surgeries (operating time greater than 4 hours).
* Patient requiring postoperative non invasive mechanical ventilation
* Patients with diagnosed COPD
* SPO2 in room air \< 96% before the intervention.
* Any patient under guardianship.
* Pre-operative and / or intra-operative morphine intake.
* Surgical management of the upper airways (ex : tonsillectomy)
* Pregnant and lactating women.
What they're measuring
1
Decrease of oxygen saturation
Timeframe: Duration of stay in post-anesthesia care unit, approximately one hour