Management of LDL-cholesterol With Inclisiran + Usual Care Compared to Usual Care Alone in Participants With a Recent Acute Coronary Syndrome

Inclusion Criteria: * Recent Acute Coronary Syndrome (in-patient/out-patient) within 5 weeks of screening * Serum LDL-C ≥70 mg/dL or non-HDL-C ≥100 mg/dL * Fasting triglycerides \<4.52 mmol/L (\<400 mg/dL) at screening * Calculated glomerular filtration rate \>20 mL/min by estimated glomerular filtration rate (eGFR) * Participants are required to be discharged on statin therapy, or have documented statin intolerance, as determined by the investigator, following hospitalization for an ACS. Statin intolerant participants are eligible if they had intolerable side effects on at least 2 different statins, including one at the lowest standard dose Exclusion Criteria: * New York Heart Association (NYHA) class IIIb or IV heart failure or last known left ventricular ejection fraction \<25%. * Significant cardiac arrhythmia within 3 months prior to randomization that is not controlled by medication or via ablation at the time of screening. * Severe concomitant non-cardiovascular disease that carries the risk of reducing life expectancy to less than 2 years. * Treatment with other investigational products or devices within 30 days or five half˗lives of the screening visit, whichever is longer. * Planned use of other investigational products or devices during the course of the study. * Treatment with monoclonal antibodies directed towards PCSK9 within 90 days of screening. * Recurrent ACS event within 2 weeks prior to randomization. * Coronary angiography and revascularization procedu…