UnknownPhase 2

Dexmedetomidine and Midazolam Nebulization as Sedation During Cesarean Delivery in Pre-eclampsia

Egypt94 participantsStarted 2021-05-15

Plain-language summary

Null hypothesis: There is no difference between the effects of nebulization of dexmedetomidine and midazolam as procedural sedation during cesarean delivery under spinal Anesthesia in pre-eclamptic parturients Alternative hypothesis: There is difference between the effects of nebulization of dexmedetomidine and midazolam as procedural sedation during cesarean delivery under spinal anesthesia in pre-eclamptic parturients

Who can participate

Age range21 Years – 38 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age: 21-38 years old. * Mild and moderate preeclampsia parturient. * American Society of AnesthesiologistPhysical status II. * Body Mass Index (BMI) (25-35kg/m²). * Type of operations: elective cesarean section under spinal anesthesia. * Written informed consent from the parturient. Exclusion Criteria: * Altered mental state. * Women with known history of allergy to study drugs. * Women with uncontrolled diabetes mellitus, bleeding, coagulation disorders, advanced hepatic, renal, cardiovascular, respiratory disease and neuropsychiatric disorders. * Patients receiving anticonvulsants or antidepressants. * Sever preeclampsia, intrauterine growth restriction or fetal compromise.

What they're measuring

Chane in the level of sedation

Timeframe: at 0 minute (immediately after nebulization) , 5 minutes then every 15 minutes intraoperative

Trial details

NCT IDNCT04873596

SponsorZagazig University

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2024-06-01

Contact for this trial

Alshaimaa Kamel, M.D

01005593169 AlshaimaaKamel80@yahoo.com

View on ClinicalTrials.gov More Procedural Sedation trials