CompletedNot Applicable

Advanced MRI Scan Before and After Radiation Therapy for the Detection of Intracranial Metastasis

United States15 participantsStarted 2021-03-30

Plain-language summary

This clinical trial studies the different types of investigational imaging techniques called sequences during magnetic resonance imaging (MRI) of the head before and after radiation therapy in patients with cancer that has spread to the brain (intracranial metastases). This clinical trial also compares these new techniques with standard MRI imaging to see if sequences provide better images. Diagnostic procedures, such as MRI, may help find and diagnose solid organ cancer and find out how far the disease has spread.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * An adult patient with pathology-proven solid organ cancer * MRI of the brain with contrast, positive for at least one intra-axial metastatic lesion greater than 5 mm * Planned treatment with stereotactic radiation Exclusion Criteria: * Contraindication to MR imaging * Known allergy to gadolinium-based contrast agents * Renal failure as defined by a glomerular filtration rate (GFR) less than 30 or the use of hemodialysis * Pregnant * Patients less than 18 years of age will be excluded

What they're measuring

Contrast to Noise Ratio

Timeframe: Participants enrolled in the study were followed for variable amounts of times (up to 2 years and 4 months) from the date of their enrollment and baseline imaging

Trial details

NCT IDNCT04870645

SponsorM.D. Anderson Cancer Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-08-29

Results submitted2024-08-30

View on ClinicalTrials.gov More Malignant Solid Neoplasm trials