RecruitingNot Applicable

rTMS Efficacy Coupled With Mirror Therapy

France64 participantsStarted 2022-10-27

Plain-language summary

Neuropathic pain is particularly difficult to treat with classic first-line drugs. Neuromodulation techniques using repetitive transcranial magnetic stimulation (rTMS) are useful alternative, but there is a need to improve their analgesic effect.Virtual reality mirror therapy has shown the capacity to alleviate pain and may be easily coupled with rTMS.The present project will investigate in individuals with neuropathic pain the effects of the rTMS coupled with virtual reality mirror therapy.

Who can participate

Age range18 Years – 85 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Clinical symptoms typical of neuropathic pain * Refractory to drug therapies * Lasting for at least 6 months, with a moderate to severe pain intensity (≥4/10 on Visual Analog Scale, VAS) and a stable pain treatment since 1month at least * Having right to health benefits Exclusion Criteria: * Ferromagnetic components and implanted microprocessors (i.e. cochlear implants) * Drug-resistant or active epilepsy, pacemaker, pregnancy, ongoing depression or personality troubles, and ongoing opioid treatment. * Any other contraindications to MRI scanner (e.g., claustrophobia, etc.).

What they're measuring

Pain intensity measurement

Timeframe: Week 9

Trial details

NCT IDNCT04867187

SponsorCentre Hospitalier Universitaire de Saint Etienne

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-12

Contact for this trial

Roland Peyron, MDPHD

(0)477825684 roland.peyron@univ-st-etienne.fr

View on ClinicalTrials.gov More Neuropathic Pain trials