Hair Transplantation for Treatment of Vitiligo (NCT04858152) | Clinical Trial Compass
WithdrawnNot Applicable
Hair Transplantation for Treatment of Vitiligo
Stopped: Logistic issues
United States0Started 2021-08-01
Plain-language summary
There are several surgical methods to treat vitiligo patches, and follicular unit extraction (FUE) is one among them. FUE, performed using punch biopsy extraction and hair follicle transplantation, has proven safe and effective in multiple studies for treatment of hair bearing (non-glabrous) skin. This technique has not yet been trialed on hairless areas (glabrous skin) affected by vitiligo, such as the lips, fingertips, knuckles, wrists, and feet, which tend to be resistant to standard treatments. We suspect this technique will be successful in patients who have responded well to other therapies in all areas except for non-hair bearing areas.
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adults 18 years and older
* Vitiligo patients already on treatment who demonstrate stable disease (have noted some repigmentation in hair bearing areas)
* Willingness to participate in the study
* Willingness to undergo biopsies of full-thickness skin tissue from areas without vitiligo and having them transplanted into areas with vitiligo
* Informed consent agreement signed by the subject
Exclusion Criteria:
* Adults unable to consent (adults lacking capacity)
* Individuals who are not yet adults (infants, children, teenagers)
* Pregnant women
* Prisoners
* Unable to return for follow-up visits
* Infection or other dermatologic condition different than vitiligo in the area to be treated
* Personal or family history of keloid formation
* Known allergies to injectable lidocaine or other topical anesthetics
* Systemic immunosuppressive medication (oral corticosteroids) within prior 4 weeks
* Topical steroids at planned recipient site within the prior 1 week
* Individuals who are unwilling to discontinue topical steroids at recipient site
* Prescription or over-the-counter medication or cosmetics containing: retinoids, glycolic acid, salicylic acid, topical steroids at the site of treatment or oral corticosteroids, or any other remedies that might affect the healing process. Non-medicated moisturizers are allowed.
* Co-existent inflammatory skin disease
* Any other condition or laboratory value that would, in the professional opinion of the investigators,…
What they're measuring
1
Percentage of patients with successful engraftment of hair follicles to transplant site
Timeframe: evaluated 10 days post-procedure visit
2
Percentage of repigmentation assessed by 4 point scale