A Study Evaluating the Safety, Tolerability, and Effect on Microvascular Obstruction of Intravenous Temanogrel in Adult Participants Undergoing Percutaneous Coronary Intervention

Inclusion Criteria: * Stable angina participants suitable for elective PCI, or participants suitable for PCI for diagnosis of non-ST-elevation myocardial infarction or unstable angina (NSTEMI/UA) who are consistently hemodynamically stable until the time of PCI and have a thrombolysis in myocardial infarction (TIMI) Flow Grade 2 or 3 on the diagnostic angiography * Target lesions for PCI must appear suitable for stenting as confirmed on the diagnostic angiography and must satisfy the study criteria regarding lesion size and vessel diameter/type. * Females must not be of childbearing potential * Males with pregnant or non-pregnant female partners of childbearing potential must agree to using a condom during treatment and for 90 days following treatment Exclusion Criteria: * Planned or anticipated use of rotational atherectomy/ablation or shockwave therapies during the PCI procedure * Any history of stroke, seizure, intracranial bleeding, or intracranial aneurysm * Transient ischemic attack within the 6 months prior to Screening * History of major trauma, major surgery, and/or clinically significant head injury or hemorrhage within the last 6 months of Screening * Any ST-elevation myocardial infarction (STEMI) within 10 days of Screening or STEMI within the target vessel territory within the last 4 months of Screening