Subthreshold Laser Treatment for Reticular Pseudodrusen Secondary to Age-related Macular Degeneration

Inclusion Criteria: * 50 years or older * Presence of RPD secondary to AMD * Best-corrected visual acuity (BCVA) between 20/20 and 20/400 inclusive * Clear ocular media * Ability to provide informed consent and attend all study visits Exclusion Criteria: * Presence of Geographic Atrophy (GA) * Evidence of choroidal neovascularization in either eye * Any prior treatment for AMD, aside from antioxidants * Any corneal opacity, cataract formation and hemorrhage in the vitreous body, which may interfere with viewing by the laser surgeon of the target structures * Aphakic eye with vitreous in the anterior chamber * Neovascular Glaucoma * Glaucoma caused by congenital angle anomalies * Open angle of less than 90º or extensive peripheral anterior and low synechia, present circumferentially around the corner * Significant corneal edema or reduced water clarity that obscures the view angle in detail * Glaucoma secondary to active uveitis * Any other ocular condition that would progress in the study period and confound visual acuity assessment * Any ocular or systemic medication known to be toxic to the lens, retina or optic nerve Presence of idiopathic or autoimmune-associated uveitis * Any intraocular surgery 3 months of entry * Any prior thermal laser in the macula * History of vitrectomy, filtering surgery, corneal transplant or retinal detachment surgery * Previous therapeutic radiation in the ocular region in either eye * Any treatment with an investigational agent in the previ…