Combined Lactobacilli (Reuteri LMG P-27481 and GG ATCC 53103) to Prevent Antibiotic Associated Symptoms in Children

Inclusion Criteria (all of the following): * Children aged 12 months to 12 years * Proven or suspected bacterial infection * Inpatient children needed antibiotic treatment * Oral or intravenous or intramuscular antibiotic administration with at least 2 days of duration * Parental informed consent to the participation to the study Exclusion Criteria: * Age below 12 months or above 12 years * Infections with no or only one day of antibiotic treatment * Sepsis or severe generalized infection * Pancreatitis * Known immunodeficiency or chronic gastrointestinal diseases or heart disease * Oncologic patients * Severe neurological impairment or lack of verbal expression * Enteral or parenteral nutrition * Gastrointestinal malformations or abdominal surgical interventions * Central line catheter * Acute or chronic diarrhea when starting antibiotics * Current or recent (in the last four weeks) use of any probiotic product * Antibiotic treatment started earlier than 24 hours before enrollment * Absence of parental consent