CompletedNot Applicable

A Community Study of the Risk for Obstructive Sleep Apnea and Respiratory Inflammation in an Adult Chinese Population

China1,270 participantsStarted 2009-05

Plain-language summary

We aimed to investigate the relationship between obstructive sleep apnea (OSA) risk and respiratory inflammation evaluated by the exhaled breath condensate （EBC）interleukin-6 IL-6 and plasma SP-D, based on the Berlin questionnaire (BQ) screening values in an adult, urban community in Beijing, China. Volunteers aged \>40 years were recruited from the Shichahai community of central Beijing. Their general information and disease history were recorded. OSA risk was assessed using the BQ. IL-6 in EBC and plasma SP-D were detected by enzyme-linked immunoassay (ELISA)through specimens collected on fasting. The differences in IL-6 and SP-D contents between high-risk and low-risk groups for OSA were compared, and the factors affecting their contents were analyzed.

Who can participate

Age range40 Years

SexALL

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Inclusion Criteria: * The inclusion criteria included individuals aged ≥40 years who had stayed in the community for at least 3 years and who had provided informed consent. Exclusion Criteria: * the exclusion criteria were patients with known severe diseases who could not cooperate in the study, such as severe psychiatric diseases, chronic liver disease, heart failure, autoimmune disease, and chronic kidney disease, and a history of pulmonary lobectomy or lung transplantation and drug abuse or alcohol addiction.

What they're measuring

Correlation between risk for OSA and inflammation

Timeframe: through study completion, an average of 3 year

Trial details

NCT IDNCT04832711

SponsorPeking University First Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2012-12