CompletedNot Applicable

Infectious Diseases in Aged Population

France521 participantsStarted 2021-04-01

Plain-language summary

The increasing number of persons \>65 years of age form a special population at risk for nosocomial and other health care-associated infections. The vulnerability of this age group is related to impaired host defenses such as diminished cell-mediated immunity. Lifestyle considerations, e.g., travel and living arrangements, and residence in nursing homes, can further complicate the clinical picture. The magnitude and diversity of health care-associated infections in the aging population are generating new arenas for prevention and control efforts. Common infections leading to hospitalizations in this age group result in respiratory infections and bacteraemia and the impact of these infections on the quality of life and disability in aged populations has not been accurately quantified in a European setting. This study aims to capture and quantify the impact of infectious diseases on quality of life in an aged population.

Who can participate

Age range65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria For Case: * Hospitalized adults 65 years or older, * Presenting with bacteremia with positive blood culture (excluding catheter related infections) and/or * WHO Severe Acute Respiratory Infection (SARI) case definition * Upper respiratory infection = SARI (fever or history of fever \>38°C, cough, onset of the disease within the last 10 days and requires hospitalisation) * Lower respiratory infection = SARI with confirmed CT/CHR * Informed consent form signed * Patient affiliated to social security insurance Exclusion Criteria For Case: * Bedridden or terminally ill patient (based upon a threshold of ADL: ≤2 TBD, or CLINICAL FRAILTY SCALE: ≥8 ) * Patients that refuse the 3- and 6-months follow-up phone call assessments * Patients that will not be able to answer the 3- and 6-months follow-up phone call assessments via a nurse * Subject in exclusion period for another study, * Subject who cannot be contacted in an emergency * Persons referred to in Articles L1121-5 to L1121-8 of the French code of public health (this corresponds to all persons protected: pregnant or parturient women, breastfeeding mothers, persons deprived of liberty by judicial or administrative decision, persons subject to a legal protection measure). Inclusion Criteria For Controls * Same age (+/- 3 years) * same sex, * without suspicion of infection * Hospitalized during the past or upcoming month in the same centre. * Informed consent form signed * Patient affiliated to social securi…

What they're measuring

Evolution of Functional dependency

Timeframe: Baseline and at 6 months

Trial details

NCT IDNCT04825132

SponsorUniversity Hospital, Grenoble

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-11-30