Previous cross-sectional studies have shown that informing cancer patients about potential chemotherapy-related cognitive symptoms may negatively affect perceived cognitive symptoms and verbal memory performance. A multicenter, randomized study in newly diagnosed breast cancer patients receiving (neo) adjuvant chemotherapy was performed to evaluate this Adverse Information Effect (AIE) over time and investigated whether inviting patients to self-affirm can reduce such AIEs on perceived cognitive symptoms and cognitive test performance.
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Between-group differences in mean change in the perceived frequency of cognitive symptoms from baseline to T1, and from baseline to T2.
Timeframe: Prior to chemotherapy-initiation (baseline; T0), six months (T1), and twelve months (T2) later
Between-group differences in mean change in the perceived severity of cognitive symptoms from baseline to T1, and from baseline to T2.
Timeframe: Prior to chemotherapy-initiation (baseline; T0), six months (T1), and twelve months (T2) later
Between-group differences in mean change in verbal memory performance from baseline to T1, and from baseline to T2.
Timeframe: Prior to chemotherapy-initiation (baseline; T0), six months (T1), and twelve months (T2) later
Between-group differences in mean change in information processing speed and executive functioning from baseline to T1, and from baseline to T2.
Timeframe: Prior to chemotherapy-initiation (baseline; T0), six months (T1), and twelve months (T2) later