Cyclosporine 0.1% Eye Drops as Prophylactic Treatment In Cataract Surgery (NCT04812951) | Clinical Trial Compass
CompletedEarly Phase 1
Cyclosporine 0.1% Eye Drops as Prophylactic Treatment In Cataract Surgery
Italy101 participantsStarted 2021-02-17
Plain-language summary
Use of Cyclosporine 0.1% Eye Drops as Prophylactic Treatment in cataract Surgery
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* \>18 years old
* Postmenopausal women for whom cataract surgery has been scheduled
* Stage N2-3; C1-2 according (Lens Opacities classification System) LOCS
* Willing to sign informed consent and fully participate to all length of the study
* Patients without any previous medical history of ocular and/or systemic inflammatory, autoimmune or auto inflammatory disease
* Patient with no history of ocular surgery
* Patients without any previous or concomitant ocular diseases
Exclusion Criteria:
* Patients under topical or systemic anti- inflammatory drugs Patients with a concomitant diagnosis of glaucoma, or on therapy with antiglaucoma drugs
* Patients on systemic or local therapy with drugs that alter the secretion of the tear film (beta blockers, antidepressants and psychotropics)
* Patients with a history of allergic, congenital, autoimmune systemic diseases
* Patients who have undergone previous eye surgery
* Ocular or peri-ocular malignancies or premalignant conditions
* Active or suspected ocular or peri-ocular infection.
* Complicated Cataract Surgery
* Patients with a positive pregnancy testAllergy or reaction history to study drug
* Patients who participated in a clinical trial in which an investigational drug was administered within 30 days or 5 half-lives of the study drug