UnknownEarly Phase 1

Ambulatory Administration of Meropenem With Elastomeric Pumps and an Isothermal Pouch

30 participantsStarted 2024-01-01

Plain-language summary

This study aims to evaluate if meropenem can be administered in outpatients as a continuous infusion using elastomeric pumps and an isothermal pouch maintaining the anti-infective solution between 10° and 15°C for improved stability.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients referred to the OPAT unit for a anti-microbial treatment with meropenem * Age ≥ 18 years * Informed consent signed Exclusion Criteria: * Patients refusing a PICC-line * Pregnancy or desire of a pregnancy * Patients considered to be not eligible for outpatient treatment by the OPAT team

What they're measuring

Proportion of plasma meropenem levels ≥ 4 mg/L

Timeframe: Will be determined at 24 hours, and then every 72 to 96 hours through treatment completion

Trial details

NCT IDNCT04809259

SponsorUniversity of Lausanne Hospitals

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-12-31

Contact for this trial

Serge de Vallière, MD, MSc

0795564312 serge.de-valliere@chuv.ch

View on ClinicalTrials.gov More Infection, Bacterial trials