Effects of Lactobacillus Plantarum PS128 in Patients With Tourette's Syndrome (NCT04805385) | Clinical Trial Compass
CompletedNot Applicable
Effects of Lactobacillus Plantarum PS128 in Patients With Tourette's Syndrome
Taiwan121 participantsStarted 2021-11-29
Plain-language summary
To evaluate whether supplementing with PS128 can improve the symptoms and quality of life related to Tourette's disease in children.
Who can participate
Age range4 Years – 18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age 4-18 years old
* Tourette's disease is diagnosed
* Make sure it is not caused by medication or other diseases
* Cause major interference in social interaction, study or work
* The healthy control group is not diagnosed with Tourette's disease, and is judged by PI
Exclusion Criteria:
* Have taken antibiotics within a month or are receiving antibiotic treatment
* Used probiotic products in powder, capsule or tablet form within two weeks (except yogurt, yogurt, Yakult and other related foods)
* Patients who have undergone hepatobiliary gastrointestinal surgery (except for colorectal polypectomy and appendectomy)
* Inflammatory bowel disease, such as Crohn's disease or ulcerative colitis
* Those with a history of cancer
* Those who are allergic to lactic acid bacteria products
* Those who are not suitable to participate judged by PI
What they're measuring
1
Yale Global Tic Severity Scale (YGTSS)
Timeframe: From Baseline to 4, 8, and 12 Weeks Assessed