Effects of Lactobacillus Plantarum PS128 in Patients With Tourette's Syndrome (NCT04805385) | Clinical Trial Compass
CompletedNot Applicable
Effects of Lactobacillus Plantarum PS128 in Patients With Tourette's Syndrome
Taiwan121 participantsStarted 2021-11-29
Plain-language summary
To evaluate whether supplementing with PS128 can improve the symptoms and quality of life related to Tourette's disease in children.
Who can participate
Age range
4 Years – 18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age 4-18 years old
* Tourette's disease is diagnosed
* Make sure it is not caused by medication or other diseases
* Cause major interference in social interaction, study or work
* The healthy control group is not diagnosed with Tourette's disease, and is judged by PI
Exclusion Criteria:
* Have taken antibiotics within a month or are receiving antibiotic treatment
* Used probiotic products in powder, capsule or tablet form within two weeks (except yogurt, yogurt, Yakult and other related foods)
* Patients who have undergone hepatobiliary gastrointestinal surgery (except for colorectal polypectomy and appendectomy)
* Inflammatory bowel disease, such as Crohn's disease or ulcerative colitis
* Those with a history of cancer
* Those who are allergic to lactic acid bacteria products
* Those who are not suitable to participate judged by PI
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Yale Global Tic Severity Scale (YGTSS)
Timeframe: From Baseline to 4, 8, and 12 Weeks Assessed