Investigators have designed a single-center randomized controlled trial to compare chlorhexidine gluconate (CHG)-impregnated dressing and standard dressing with respect to their effects on the infection outcomes. The study was condcuted in the pediatric intensive care unit in the 18 months period.
Who can participate
Age range1 Month – 17 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* being aged age less than 18 years old,
* providing informed consent to participate in the study
* insertion of a short term non-tunneled, percutaneously inserted CVC (jugular, subclavian, or femoral) that would remain in place for greater than 48 hours during PICU admission.
Exclusion Criteria:
Patients were excluded if they:
* had known allergies to CHG-impregnated or standard dressing,
* would receive insertion of any other type of CVC device (e.g., peripherally inserted CVC, tunneled CVC), were included in the study previously,
* had a current BSI (positive blood culture within 48 hours),
* had received CVC insertion within the 30 days prior to PICU admission.
Additionally, investigators also excluded patients in which
* catheterization had not been performed by the PICU specialist,
* those that were discharged from the PICU with indwelling CVC,
* patients who received extracorporeal membrane oxygenation,
Individuals in which the following events were recorded:
* Accidental catheter removal,
* CVC removal before 48 hours, and
* death within 48 hours after CVC insertion.
In the event that a patient required CVC re-insertion after the initial catheter was removed (due to any reason), only the first application was included in the study -given that any other exclusion criteria did not exclude the patient. Finally, if a patient required catheter reinsertion before the completion of the 48-hour catheter-infection monitoring of the initial applicat…