Adolescence is a time of heightened reward sensitivity and greater impulsivity. On top of this, many teenagers experience chronic sleep deprivation and misalignment of their circadian rhythms due to biological shifts in their sleep/wake patterns paired with early school start times. Many studies find that this increases the risk for substance use (SU). However, what impact circadian rhythm and sleep disruption either together or independently have on the neuronal circuitry that controls reward and cognition, or if there are interventions that might help to modify these disruptions is unknown. Project 2 (P2) of the CARRS center will test an innovative and mechanistic model of brain circuitry that uses multi-method approaches, takes a developmental perspective, and incorporates key sleep and reward constructs.
Age range
13 Years – 15 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Weekday Sleep Duration--Actigraphy & Diaries
Timeframe: Baseline (2 Weeks), T2 (2 weeks)
Circadian Timing-Dim Light Melatonin Onset
Timeframe: Baseline Overnight Visit (T1) & T2 Overnight Visit(2 weeks later). Always on a Friday.
Circadian Alignment
Timeframe: Baseline overnight (T1), T2 overnight (2 weeks after T1)
Reward motivation (Behavioral)
Timeframe: Baseline overnight (T1) vs. T2 overnight (2 weeks after T1)
Behavioral Inhibition
Timeframe: Baseline overnight (T1) vs. T2 overnight (2 weeks after T1). Always on a Friday.
Neural correlates of Impulse control
Timeframe: Baseline overnight (T1) vs. T2 overnight (2 weeks after T1). Always on a Friday.
Neural correlates of Reward Anticipation
Timeframe: Baseline overnight (T1) vs. T2 overnight (2 weeks after T1). Always on a Friday.
Neural Correlates of Reward Receipt
Timeframe: Overnight visits at end of T1 & T2 (two weeks after T1)