PHASE 1 SARS-COV-2-Spike-Ferritin-Nanoparticle (SpFN) Vaccine With ALFQ Adjuvant for Prevention of COVID-19

Inclusion Criteria: * Must be a male or non-pregnant, non-breastfeeding female between the ages of 18 and 55 years, inclusive, at the time of enrollment. * Must be willing and able to read, sign, and date the informed consent document. * Must demonstrate an understanding of the study with a passing score (90% or greater) on the Test of Understanding (TOU) by the third attempt, before study-related procedures are performed. * Must be willing and able to comply with study requirements and be available for follow-up visits for the entire study. * Must have the means to be contacted by telephone and/or video for remote follow-up visits as needed. * Must have a body mass index (BMI) ≥18.1 kg/m2 and \<35.0 kg/m2. * Have no previously documented COVID-19/SARS-CoV-2 infection * Must agree to refrain from donating blood or plasma outside of this study for the duration of participation in this study. * Must have acceptable screening laboratory findings: white blood cell (WBC), hemoglobin, platelet count, prothrombin (PT), prothrombin time (PTT), aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP), creatinine, and total bilirubin) within 14 days before Study Day 1. * Must be healthy based on the physician investigator's clinical judgment after review of past medical history, medication use, vital signs, and an abbreviated physical examination. * Biological females must have a negative urine pregnancy test at screening and a negative urine pregnancy test…