Efficacy and Safety of ETX-018810 in Subjects With Lumbosacral Radicular Pain

Inclusion Criteria: * The subject has pain consistent with a diagnosis of chronic lumbosacral radiculopathy due to injury of the lumbosacral nerve root(s) * The subject reports at least moderate pain intensity at screening. * The subject's onset of leg pain due to LSRP is at least 3 months * The subject has a magnetic resonance imaging (MRI) scan that is normal or shows incidental lesions * The subject has a calculated creatinine clearance ≥30 mL/min * The subject has clinical laboratory values within normal limits or abnormal values that the investigator deems not clinically significant. * body mass index (BMI) \<40 kg/m2. Exclusion Criteria: * The subject has previously undergone back surgery * The subject is unable to reliably delineate or assess pain by anatomical location/distribution on a body map. * The subject has a history of peripheral neuropathy, evidence of peripheral neuropathy, or evidence of mononeuropathy in the same limb of LSRP. * The subject has pain due to infection/abscess, hematoma, or malignancy or other pain that may interfere with the assessment of LSRP in the legs. * The subject has clinically significant and/or unstable renal, hepatic, hematologic, endocrine, immunologic, inflammatory/rheumatologic, respiratory, or cardiovascular disease that would compromise participation in the study * The subject has any neurological disease that could interfere with participation in the study (e.g., Huntington's disease, Parkinson's disease, Alzheimer's disea…