Total Post-thyroidectomy Hypocalcemia After Preoperative Cholecalciferol Supplementation (NCT04775381) | Clinical Trial Compass
RecruitingPhase 3
Total Post-thyroidectomy Hypocalcemia After Preoperative Cholecalciferol Supplementation
France200 participantsStarted 2021-06-30
Plain-language summary
This prospective study evalue the inflence of pre operative vit D3 administration on post operative hypocalcemia in patients undergoing Total thyroidectomy
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patient ≥ 18 years old
* Patient shall be operated on for a total thyroidectomy in one time for any indication
* Written informed consent (IC) obtained
* Patients with affiliation to the social security system
Exclusion Criteria:
• Medical history of : Thyroid or parathyroid surgery Hyperparathyroidism Granulomatosis flare-up
* Hypocalcemia, hypercalcemia/ hypercalciuria, or symptom of Hypocalcemia, hypercalcemia/ hypercalciuria, not due to thyroid pathologies
* Chronic kidney disease grade ≥4
* Severe liver failure
* 25OHD supplementation within last 3 months before surgery
* Malabsorption syndrome
* Known hypersensitivity to vitamin D
* Medical history of calcic lithiasis
* Pregnant women
* Vulnerable populations (guardianship or trusteeship)
* Allergies to one of the components of the fruit juice
What they're measuring
1
Assessment of the effect of pre-operative cholecalciferol supplementation on the occurrence of post-operative hypocalcemia after total thyroidectomy