Eptinezumab in Adults With Migraine and Medication Overuse Headache

Inclusion Criteria: * The patient has a diagnosis of migraine as defined by International Headache Society (IHS) International Classification of Headache Disorders (ICHD)-3 guidelines confirmed at the Screening Visit with a history of migraine onset of at least 12 months prior to the Screening Visit. * The patient has ≥8 migraine days per month for each month on average within the past 3 months prior to the Screening Visit. * The patient has a diagnosis of medication overuse headache (MOH) as defined by IHS ICHD-3 guidelines. * The patient has headache on ≥15 days/month for each month within the past 3 months prior to the Screening Visit. * The patient has regular overuse of one or more drugs that can be taken for acute and/or symptomatic treatment of headache, for \>3 months. * The patient has ≥15 to ≤26 headache days, of which ≥8 days were assessed as migraine days during the Screening Period, based on prospectively collected information in the eDiary. * The patient overuses drugs that can be taken for acute and/or symptomatic treatment of headache during the Screening Period, based on prospectively collected information in the eDiary. * The patient has demonstrated compliance with the Headache eDiary by entry of data for at least 24 of the 28 days of the Screening Period. * The patient has had an onset of migraine at \<50 years of age Exclusion Criteria: * The patient has experienced failure on a previous treatment targeting the calcitonin gene-related peptide (CGRP) pa…