CompletedNot Applicable

Method of Early Diagnosis of Laryngopharyngeal Reflux

Kazakhstan385 participantsStarted 2021-01-10

Plain-language summary

The investigator will issue a Patient Information Consent for the participant in the study. 1.Patients will be asked to complete the Reflux Symptom Index questionnaire. Clinical survey, medical history. 2. Objective methods for assessing the patient's condition: \- examination of ENT organs. 3. Laboratory and instrumental research methods: Endoscopic laryngoscopy and video laryngoscopy, pH-metry, acoustic voice analysis. 4.Sociological method. 5. Subjective methods for assessing the condition of the larynx. 6. Аnalysis of the received data

Who can participate

Age range

18 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patient's informed consent * Age: 18-75 years old * No serious somatic diseases. * Patients with complaints of sore throat, coughing, burning sensation in the throat, coughing, frequent sore throat, difficulty swallowing, lump in the throat, foreign body feeling in the throat, voice changes, heartburn and belching. * Diagnosis: Chronic pharyngitis * Chronic laryngitis Exclusion Criteria: * Disagreement to participate in scientific research * Age: under 18 and over 76 * Severe somatic diseases, organic lesions of the gastrointestinal tract and ENT organs * Patients with pulmonary pathologies * Patients with allergic manifestations (seasonal hay fever, asthma, etc.) * With diagnoses: Acute respiratory diseases * Patients with general neuralgic disorders

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Acidity level of the main group, Week 0

Timeframe: at the inclusion to the study

Acidity level of the control group 1, Week 0

Timeframe: at the inclusion to the study

Acidity level of the control group 2, Week 0

Timeframe: at the inclusion to the study

"Index of reflux symptoms" of the main group, Week 0

Timeframe: at the inclusion to the study

"Index of reflux symptoms" of the control group 1, Week 0

Timeframe: at the inclusion to the study

"Index of reflux symptoms" of the control group 2, Week 0

Timeframe: at the inclusion to the study

Endoscopic laryngoscopy of the main group, Week 0

Timeframe: at the inclusion to the study

Trial details

NCT IDNCT04771221

SponsorKazakh Medical University of Continuing Education

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-02-15

View on ClinicalTrials.gov More Laryngopharyngeal Reflux trials

Plain-language summary

Who can participate

Age range

18 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Acidity level of the main group, Week 0

Timeframe: at the inclusion to the study

Acidity level of the control group 1, Week 0

Timeframe: at the inclusion to the study

Acidity level of the control group 2, Week 0

Timeframe: at the inclusion to the study

"Index of reflux symptoms" of the main group, Week 0

Timeframe: at the inclusion to the study

"Index of reflux symptoms" of the control group 1, Week 0

Timeframe: at the inclusion to the study

"Index of reflux symptoms" of the control group 2, Week 0

Timeframe: at the inclusion to the study

Endoscopic laryngoscopy of the main group, Week 0

Timeframe: at the inclusion to the study