UnknownNot Applicable

Respiratory Aerosols in Patients With COVID-19 and Healthy Controls

Germany525 participantsStarted 2021-01-18

Plain-language summary

The proposed study will investigate respiratory aerosols in SARS-CoV-2 (Severe Acute Respiratory Syndrome Corona Virus 2) positive and negative children and adults with the Resp-Aer-Meter (Palas GmbH). For this purpose, first, the measurement of respiratory aerosols (particle sizes and concentration) with the Resp-Aer-Meter will be established. Thereafter, a comparison between polymerase chain reaction (PCR) SARS-CoV-2 positive and negative participants (children and adults) will be conducted. In addition to the measurement of aerosols, the clinical symptoms, lung function (FEV1) and laboratory inflammatory markers will be analyzed.

Who can participate

Age range6 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age 6 years or older * SARS-CoV-2 PCR testing within the last 3 days * Ability to capture extend and consequences of the study * Written informed consent of patient and, if applicable, of caregiver Exclusion Criteria: * Age under 6 years * Inability to participate in aerosol measurement * Inability to participate in Spirometry * Inability to capture extend and consequences of the study * Only for arm 1 (PCR SARS-CoV-2 negative adults): chronic disease with immunosuppressive therapy

What they're measuring

Aerosol concentration in PCR SARS-CoV-2 positive and negative participants

Timeframe: Each patient visit will take about 1-2 hours.

Trial details

NCT IDNCT04739020

SponsorJohann Wolfgang Goethe University Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-12-30

Contact for this trial

Desiree Gutmann, MD

004915117190498 desiree.gutmann@kgu.de

View on ClinicalTrials.gov More SARS-CoV-2 Infection trials