The purpose of this study is to assess the safety, reactogenicity, immunogenicity and long-term persistence of immune response up to 5 years following a single dose vaccination of GSK's investigational vaccine RSVPreF3 OA, in adults aged 60 years and above. The study will also evaluate the immunogenicity, safety and reactogenicity of additional vaccine doses given according to different revaccination schedules.
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Humoral Immune Response in Terms of Respiratory Syncytial Virus (RSV)-A Neutralizing Antibody Geometric Mean Titers (GMTs) at Day 1
Timeframe: At Day 1
Humoral Immune Response in Terms of RSV-A Neutralizing Antibody GMTs at Day 31
Timeframe: At Day 31
Humoral Immune Response in Terms of RSV-A Neutralizing Antibody GMTs at Month 6
Timeframe: At Month 6
Humoral Immune Response in Terms of RSV-A Neutralizing Antibody GMTs at Month 12
Timeframe: At Month 12
Humoral Immune Response in Terms of RSV-B Neutralizing Antibody Titers at Day 1
Timeframe: At Day 1
Humoral Immune Response in Terms of RSV-B Neutralizing Antibody Titers at Day 31
Timeframe: At Day 31
Humoral Immune Response in Terms of RSV-B Neutralizing Antibody Titers at Month 6
Timeframe: At Month 6
Humoral Immune Response in Terms of RSV-B Neutralizing Antibody Titers at Month 12
Timeframe: At Month 12