Tolerability of Device Based Therapies for Neurofibromatosis Type 1 Cutaneous Neurofibromas

Inclusion Criteria: * Adult males and females ≥18 years of age * Have a diagnosis of Neurofibromatosis Type 1 * Patients must be seeking treatment for cutaneous Neurofibromas * Patients must have ≥ 6 paired cutaneous Neurofibromas (3 to be treated and 3 untreated) that are visible and measure between 2-4mm in size. * Able and willing to comply with all visit, treatment and evaluation schedules and requirements * Able to understand and provide written informed consent * Access to a Smart Phone to be able to take and upload photographs to an application Exclusion Criteria: * Patients who are undergoing other treatment modalities or investigational agents for their cNF lesions * Individuals who cannot give informed consent or adhere to study schedule * Actively tanning during the course of the study * Adverse reactions to compounds of any external agent (e.g., gels, lotions or anesthetic creams) required for use in the study, if no alternative to the said agent exists; * Known allergy to injectable anesthetics or deoxycholic acid * Any condition which, in the Investigator's opinion, would make it unsafe (for the participant or study personnel) to treat the participant as part of this research study; * Pregnant females, due to possible discomfort with the procedure even though the procedure is localized and there is no new drug.