Progesterone as Luteal Support in Frozen IVF Natural Cycles (NCT04725864) | Clinical Trial Compass
UnknownPhase 4
Progesterone as Luteal Support in Frozen IVF Natural Cycles
Sweden1,800 participantsStarted 2021-05-01
Plain-language summary
The ProFET study aims to investigate if luteal phase support by vaginal progesterone, is superior to no luteal phase support, in terms of live birth rate per woman after a frozen embryo transfer (FET), in a natural cycle (NC) after in-vitro fertilization (IVF), and if 7 weeks of treatment is superior to 3 weeks duration.
Who can participate
Age range18 Years – 43 Years
SexFEMALE
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Planned for a FET-NC with a blastocyst
* BMI \>18.5 \<35
* Regular menstrual cycles 24-35 days
* Given informed consent
* Understand written and spoken Swedish, English or Arabic
Exclusion Criteria:
* Oocyte donor cycles, preimplantation genetic testing (PGT) cycles. Uterine malformation, submucous myoma and endometrial polyps.
* Hypersensitivity against study medication. Other contraindications according to www.fass.se
* Development of serious disease contraindicating ART or pregnancy.
* Participation or recent participation in a clinical study with an investigational product (past 30 days). Previous participation in this study.