Evaluation of Safety, Tolerability and Immune Responses of Ebola-S and Marburg Vaccines in Healthy Adults

Inclusion Criteria: * Male or female participant must be between 18-50 (inclusive) years of age; * Meet criteria for plasma donation\*; * Available for clinic follow-up through Day 99 and one additional follow-up call on Day 181 (±14 days); * Agrees not to receive any vaccine from day of enrollment through Day 99; * Able to provide proof of identity to the satisfaction of the study clinician completing the enrollment process; * Agree to have photos taken of the vaccination site, if indicated ; * Willing to complete repeated plasmapheresis and other protocol requirements; * Must complete an Assessment of Understanding (AoU) by answering 9 out of 10 questions correctly at least once in 3 attempts; * Willing to donate blood for sample storage and future unspecified assay development; * Able to read (English) and willing to complete informed consent process; * In good general health without clinically significant medical history, based on medical history, physical examination, vital signs and clinical laboratory results; * Physical examination and laboratory results without clinically significant findings and a body mass index (BMI) ≥ 17 and ≤ 35 within the 28 days prior to vaccination; * Laboratory Criteria within 28 days prior to vaccination (normal per testing laboratory) for: complete blood count (CBC) with differential count, alanine aminotransferase (ALT), serum creatinine and total protein; * Serology screen negative for infectious diseases (hepatitis B, hepatitis C, HIV,…