Adipose Derived Mesenchymal Cell Treatment in Lungtransplantation

Inclusion Criteria: * Male or female lung recipients 18-70 years of age undergoing primary double (including size reduction) lung transplantation. * Patient willing and capable of giving written informed consent for study participation and anticipated to be able to participate in the study for 3 months. Exclusion Criteria: * Recipients of multi-organ transplant, and or previously transplanted with any solid organ, including previous lung transplantation. * Patients scheduled for single lung transplantation. * Patients in need of acute transplantation e.g. patients on urgent call for transplantation and patients on respirator or on extra corporal membrane oxygenation (ECMO) treatment at time of transplantation. * Patients that based on crossmatch prior to transplantation have need for additional immunosuppressive treatment * Donor lung cold ischemic time \> 12 hours. * Patients with platelet count \< 50,000/mm3 at the evaluation before transplantation. * Patients who are unlikely to comply with the study requirements. * Patient unable to participate in the study for the full study period * Patients with any past (within the past 3-5 years) or present malignancy (other than excised basal cell carcinoma). * Females capable of becoming pregnant must have a negative pregnancy test prior to transplantation. After inclusion, they must use contraceptives for 2 months following the given stem cell treatment. The pill, spiral, depot injection of progesterone, sub-dermal implantation…