The purpose of this study was to assess immunogenicity and safety of MenABCWY vaccine in healthy adolescents and adults aged 15 to 25 years previously vaccinated with MenACWY vaccine.
Age range
15 Years – 25 Years
Sex
ALL
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Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Percentages of Participants With a 4-fold Rise in Human Serum Bactericidal Assay (hSBA) Titers Against N. Meningitidis Serogroups A, C, W, and Y at 1 Month After the Second MenABCWY Vaccination and the Single MenACWY Vaccination, Relative to Baseline
Timeframe: At 1 month after vaccination schedule (i.e., Day 211 for ABCWY group and Day 31 for ACWY group) compared to Day 1 (Baseline)
Percentages of Participants With a 4-fold Rise in hSBA Titers Against N. Meningitidis Serogroups A, C, W, and Y at 1 Month After the First MenABCWY Vaccination and the Single MenACWY Vaccination, Relative to Baseline
Timeframe: At 1 month after the first vaccination (i.e., Day 31) compared to Day 1 (Baseline)
Number of Participants With Solicited Administration Site Events Following Vaccination at Day 1 for ABCWY Group and ACWY Group
Timeframe: During the 7 days (including day of vaccination) following vaccination at day 1 for ABCWY group and ACWY group
Number of Participants With Solicited Administration Site Events Following Vaccination at Day 181 for ABCWY Group
Timeframe: During the 7 days (including day of vaccination) following vaccination at Day 181 for ABCWY group
Number of Participants With Solicited Systemic Events Following Vaccination at Day 1 for the ABCWY Group and ACWY Group
Timeframe: During the 7 days (including day of vaccination) following vaccination at day 1 for the ABCWY group and ACWY group
Number of Participants With Solicited Systemic Events Following Vaccination at Day 181 for the ABCWY Group
Timeframe: During the 7 days (including day of vaccination) following vaccination at day 181 for the ABCWY group
Number of Participants With Any Unsolicited Adverse Events (AEs) (Including All Serious Adverse Events [SAEs], AEs Leading to Withdrawal, AEs of Special Interest [AESIs] and Medically Attended AEs)
Timeframe: During the 30 days (including day of vaccination) following vaccination at day 1 for ABCWY group and ACWY group
Number of Participants With Any Unsolicited Adverse Events (AEs) (Including All Serious Adverse Events [SAEs], AEs Leading to Withdrawal, AEs of Special Interest [AESIs] and Medically Attended AEs) Following Vaccination at Day 181 for ABCWY Group
Timeframe: During the 30 days (including day of vaccination) following vaccination at day 181 for ABCWY group
Number of Participants With SAEs, AEs Leading to Withdrawal, AESIs and Medically Attended AEs
Timeframe: From Day 1 to Day 361 (throughout the study period)