The purpose of this study is to demonstrate that treatment with BMS-986012 in combination with carboplatin, etoposide, and nivolumab will have acceptable safety and tolerability and will improve progression-free survival compared with carboplatin, etoposide, and nivolumab alone in newly diagnosed participants with extensive-stage small cell lung cancer (ES-SCLC).
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Incidence of adverse events (AEs)
Timeframe: Up to 2 years and 100 days
Incidence of serious adverse events (SAEs)
Timeframe: Up to 2 years and 128 days
Incidence of AEs leading to discontinuation
Timeframe: Up to 2 years and 128 days
Incidence of deaths
Timeframe: Up to 2 years and 128 days
Progression-free survival (PFS) by blinded independent central review (BICR) based on Response Evaluation Criteria in Solid Tumors (RECIST) v1.1 criteria
Timeframe: Up to 2 years