Walking Pattern Characteristics in Normal Pressure Hydrocephalus (NCT04702035) | Clinical Trial Compass
CompletedNot Applicable
Walking Pattern Characteristics in Normal Pressure Hydrocephalus
Switzerland60 participantsStarted 2018-01-01
Plain-language summary
20 patients who are diagnosed with NPH receive a set of 5 wearable gyroscopes (IMUs, ZurichMove sensors) for a period of 3 days for measurement and characterization of their walking in an ambulatory setting. At a follow-up 2 weeks to 6 months after CSF diversion surgery, the examination is repeated and improvement is measured. The data will be compared with a healthy group of 20 age- and gender-matched individuals as well a a group of 20 young individuals.
Who can participate
Age range18 Years – 100 Years
SexALL
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Inclusion criteria
✓. Informed Consent as documented by signature prior to any study related procedures or informed consent by a legal representative in case of cognitive deficits.
✓. Male and female patients alike
✓. Age between 60 and 100 years
✓. Clinical suspect for NPH
✓. Significant improvement (by more than 10%) in walking speed or endurance in a standardized CSF-TAP test (of at least 35 ml CSF).
✓. Planned implantation of a VP shunt for NPH treatment (independently from the study).
✓. Informed Consent as documented by signature prior to any study related procedures
✓. Male and female patients alike (matched to group 1)
Exclusion criteria
✕. Enrolment of the investigator, his/her family members, employees and other dependent persons (only for patients; no exclusion criteria for controls),
✕. Apparent or suspected movement disorder or other known disorder, which might affect normal standing or walking
✕. Cardiovascular disorders, which might affect physical resilience
✕. Pregnant women
✕. Pre-menopausal state of female patients and probands in groups 1 and 2.
What they're measuring
1
Walking characteristics
Timeframe: Between 2 weeks to 6 months after CSF diversion surgery